STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRDX4Peroxiredoxin 4. (251 aa)    
Predicted Functional Partners:
TXNDC5
Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family.
  
 0.883
PRDX5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.868
PDIA6
Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family.
  
 0.863
ERP44
Endoplasmic reticulum protein 44.
  
 0.857
SRXN1
Sulfiredoxin 1.
   
 0.795
TXNDC8
Thioredoxin domain containing 8.
  
 0.781
TXN
Thioredoxin.
  
 0.764
TXNDC2
Thioredoxin; Belongs to the thioredoxin family.
  
 0.764
TAF11
TAFII28 domain-containing protein.
      
 0.758
NME8
NME/NM23 family member 8.
  
 0.757
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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