Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GATA3GATA binding protein 3. (443 aa)    
Predicted Functional Partners:
TBX21
T-box transcription factor 21.
    
 0.986
FOXA1
Forkhead box A1.
   
 0.977
TAL1
TAL bHLH transcription factor 1, erythroid differentiation factor.
   
 0.951
EP300
E1A binding protein p300.
    
 0.943
ESR1
NR LBD domain-containing protein.
    
 0.908
NRIP1
Nuclear receptor interacting protein 1.
     
 0.898
FOXA2
Forkhead box A2.
   
 0.897
FOXP3
Forkhead box P3.
    
 
 0.885
STAT6
Signal transducer and activator of transcription.
   
 0.849
GATA2
GATA binding protein 2.
    
 0.837
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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