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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DBHDopamine beta-hydroxylase. (620 aa)    
Predicted Functional Partners:
PNMT
Phenylethanolamine N-methyltransferase.
   
 
 0.962
TOMT
Uncharacterized protein.
     
 0.955
DDC
Dopa decarboxylase.
   
 
 0.950
MAOB
Amine oxidase.
   
 
 0.948
MAOA
Amine oxidase.
   
 
 0.946
AOC3
Amine oxidase.
     
 0.900
PRSS58
Serine protease 58.
      
 0.770
TH
Tyrosine hydroxylase.
   
  
 0.726
TAS1R3
Taste 1 receptor member 3.
      
 0.701
PAH
Phenylalanine hydroxylase.
   
  
 0.639
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.