STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFDNAfadin, adherens junction formation factor. (1501 aa)    
Predicted Functional Partners:
NECTIN3
Nectin cell adhesion molecule 3.
    
 0.891
NECTIN1
Nectin cell adhesion molecule 1.
    
 0.882
TJP1
Tight junction protein 1; Belongs to the MAGUK family.
   
 
 0.811
TJP2
Uncharacterized protein; Belongs to the MAGUK family.
   
 
 0.795
F11R
F11 receptor.
    
 0.793
REM1
GTP-binding protein; Belongs to the small GTPase superfamily. RGK family.
    
 
 0.768
VCL
Vinculin.
    
 
 0.751
CTNND1
Catenin delta 1.
      
 0.697
TJP3
Tight junction protein 3; Belongs to the MAGUK family.
   
 
 0.694
G3T8F1_LOXAF
Myosin_tail_1 domain-containing protein.
      
 0.659
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.