Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFDNAfadin, adherens junction formation factor. (1501 aa)    
Predicted Functional Partners:
NECTIN3
Nectin cell adhesion molecule 3.
    
 0.987
NECTIN1
Nectin cell adhesion molecule 1.
    
 0.979
TJP1
Tight junction protein 1; Belongs to the MAGUK family.
   
 0.969
TJP2
Uncharacterized protein; Belongs to the MAGUK family.
   
 0.969
F11R
F11 receptor.
    
 0.940
RAP1A
RAP1A, member of RAS oncogene family.
    
 0.938
KRAS
KRAS proto-oncogene, GTPase.
    
 0.933
SSX2IP
SSX family member 2 interacting protein.
    
 0.933
MRAS
Muscle RAS oncogene homolog.
    
 0.924
CTNNA3
Catenin alpha 3.
   
 0.922
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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