Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CDK14Cyclin dependent kinase 14; Belongs to the protein kinase superfamily. (469 aa)    
Predicted Functional Partners:
CDKN1A
Cyclin dependent kinase inhibitor 1A.
   
 0.866
CDK17
Cyclin dependent kinase 17.
    
   0.800
CCNY
CYCLIN domain-containing protein; Belongs to the cyclin family.
   
 
 0.759
CCNYL1
Cyclin Y like 1; Belongs to the cyclin family.
   
 
 0.759
G3ULH2_LOXAF
CYCLIN domain-containing protein; Belongs to the cyclin family.
   
 
 0.759
RB1
RB transcriptional corepressor 1.
   
 0.710
CDKN1B
Cyclin dependent kinase inhibitor 1B.
   
 0.675
TMEM268
Transmembrane protein 268.
      
 0.664
MCM4
DNA helicase; Belongs to the MCM family.
   
 0.663
CDK5
Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.
   
   0.662
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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