STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NDRG1N-myc downstream regulated 1. (384 aa)    
Predicted Functional Partners:
NDRG2
NDRG family member 2.
    
   0.810
SLC7A5
Solute carrier family 7 member 5.
   
 
 0.784
MYCN
MYCN proto-oncogene, bHLH transcription factor.
    
 
 0.736
ASCL2
Achaete-scute family bHLH transcription factor 2.
      
 0.692
SGK3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 
 0.681
NDRG4
NDRG family member 4.
    
   0.665
MYC
Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
    
 
 0.628
TSC2
TSC complex subunit 2.
      
 0.609
SGK1
Non-specific serine/threonine protein kinase.
    
 
 0.601
ZFHX4
Zinc finger homeobox 4.
      
 0.592
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.