STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
JUPJunction plakoglobin. (741 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
  
0.997
DSG2
Desmoglein 2.
   
 0.989
PKP2
Plakophilin 2.
   
 0.986
DSG1
Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
 0.982
APC
APC regulator of WNT signaling pathway.
   
 0.980
CDH3
Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.976
CDH1
Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.976
CDH11
Cadherin 11; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.973
CTNND1
Catenin delta 1.
   
 0.972
PKP1
Plakophilin 1.
   
 0.960
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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