STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JUPJunction plakoglobin. (741 aa)    
Predicted Functional Partners:
CDH1
Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.983
LEF1
Lymphoid enhancer binding factor 1.
    
 0.974
TCF7
Transcription factor 7.
    
 0.974
CTNNB1
Catenin beta 1.
  
 
0.967
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.950
CTNNBIP1
Catenin beta interacting protein 1.
    
 0.932
CDH5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.913
PKP2
Plakophilin 2.
   
 0.908
CCDC130
Coiled-coil domain containing 130.
   
   0.908
APC2
APC regulator of WNT signaling pathway 2.
   
 0.904
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.