STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPM1LProtein phosphatase, Mg2+/Mn2+ dependent 1L. (228 aa)    
Predicted Functional Partners:
BCKDHB
Branched chain keto acid dehydrogenase E1 subunit beta.
    
 0.685
VAPA
VAMP associated protein A.
   
 0.646
AANAT
Aralkylamine N-acetyltransferase.
    
   0.636
BCKDHA
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 0.620
DBT
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
    
 0.618
VAPB
VAMP associated protein B and C.
   
 0.569
TBC1D16
Rab-GAP TBC domain-containing protein.
      
 0.519
MTFMT
Mitochondrial methionyl-tRNA formyltransferase.
  
   0.487
MCF2L2
CRAL-TRIO domain-containing protein.
    
 
 0.470
SMC4
Structural maintenance of chromosomes protein.
  
  
 0.469
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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