STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PPM1LProtein phosphatase, Mg2+/Mn2+ dependent 1L. (228 aa)    
Predicted Functional Partners:
ACBD3
Acyl-CoA binding domain containing 3.
   
  
 0.833
BCKDHB
Branched chain keto acid dehydrogenase E1 subunit beta.
    
 0.710
RAB33B
RAB33B, member RAS oncogene family.
   
  
 0.707
DBT
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
    
 0.702
CSTF1
Cleavage stimulation factor subunit 1.
      
 0.684
BCKDHA
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 0.680
VAPA
VAMP associated protein A.
   
 0.674
TBC1D16
Rab-GAP TBC domain-containing protein.
      
 0.653
LRRC34
Leucine rich repeat containing 34.
   
 0.632
MCF2L2
CRAL-TRIO domain-containing protein.
    
 
 0.618
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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