Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP10Rho GTPase activating protein 10. (785 aa)    
Predicted Functional Partners:
C2CD2
C2 calcium dependent domain containing 2.
    
   0.927
ARHGAP26
Rho GTPase activating protein 26.
    
 
 0.927
CTNNB1
Catenin beta 1.
     
  0.870
PAK2
Non-specific serine/threonine protein kinase.
    
 0.866
PKN3
Protein kinase N3.
    
 0.759
BRK1
BRICK1 subunit of SCAR/WAVE actin nucleating complex.
    
 0.734
NCKAP1L
NCK associated protein 1 like.
   
 0.680
NCKAP1
NCK associated protein 1.
   
 0.680
CDC42
Uncharacterized protein.
    
 0.671
CYFIP2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 0.655
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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