STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GCH1GTP cyclohydrolase 1. (250 aa)    
Predicted Functional Partners:
GCHFR
GTP cyclohydrolase I feedback regulator.
    
 0.995
PTS
Uncharacterized protein.
  
 
 0.958
MOCS1
Molybdenum cofactor synthesis 1.
  
 
 0.918
GUCY2C
Guanylate cyclase.
     
 0.906
NME2
Nucleoside diphosphate kinase.
   
 0.881
NME1
Nucleoside diphosphate kinase.
   
 0.881
NME4
NME/NM23 nucleoside diphosphate kinase 4; Belongs to the NDK family.
   
 0.880
NME7
Nucleoside diphosphate kinase 7; Belongs to the NDK family.
   
 0.879
NME6
Nucleoside diphosphate kinase.
   
 0.879
GUCY1A1
Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
     
 0.878
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: medium (46%) [HD]