STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)    
Predicted Functional Partners:
PDPK1
3-phosphoinositide dependent protein kinase 1.
  
0.982
TSC1
TSC complex subunit 1.
    
 0.972
FOXO3
Forkhead box O3.
    
 0.971
FOXO1
FOXO-TAD domain-containing protein.
    
 0.971
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 0.971
FOXO4
Forkhead box O4.
    
 0.971
MDM2
E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.
    
 0.969
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
0.967
TSC2
TSC complex subunit 2.
    
 0.966
TRIB3
Tribbles pseudokinase 3.
 
 
0.965
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.