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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOX6SRY-box transcription factor 6. (827 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
   
 0.719
SOX5
SRY-box transcription factor 5.
  
 
 
0.703
DMRT1
Uncharacterized protein.
  
 
 
 0.660
JUP
Junction plakoglobin.
   
 0.622
BCL11A
BAF chromatin remodeling complex subunit BCL11A.
    
 
 0.597
CYP19A1
Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family.
   
  
 0.575
ACAN
Aggrecan.
    
 
 0.568
GATA1
GATA binding protein 1.
    
 
 0.565
TRIP12
Thyroid hormone receptor interactor 12.
    
 
 0.554
FOXJ3
Forkhead box J3.
    
 
 0.538
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.