KBTBD8 protein (Loxodonta africana) - STRING interaction network

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KBTBD8

Kelch repeat and BTB domain containing 8. (493 aa)

Predicted Functional Partners:

CUL3

0.952

TCOF1

0.849

PKN1

0.824

KLHL29

0.807

AGO2

0.782

NOLC1

0.780

LRRC19

0.741

CUL1

0.697

COMMD9

0.661

COMMD5

0.661

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO2	CUL3	ENSLAFP00000010792	ENSLAFP00000002647	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Cullin 3; Belongs to the cullin family.	0.580
AGO2	KBTBD8	ENSLAFP00000010792	ENSLAFP00000002437	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Kelch repeat and BTB domain containing 8.	0.782
COMMD5	COMMD9	ENSLAFP00000008820	ENSLAFP00000001173	COMM domain containing 5.	COMM domain containing 9.	0.978
COMMD5	CUL1	ENSLAFP00000008820	ENSLAFP00000002838	COMM domain containing 5.	Cullin 1; Belongs to the cullin family.	0.429
COMMD5	CUL3	ENSLAFP00000008820	ENSLAFP00000002647	COMM domain containing 5.	Cullin 3; Belongs to the cullin family.	0.546
COMMD5	KBTBD8	ENSLAFP00000008820	ENSLAFP00000002437	COMM domain containing 5.	Kelch repeat and BTB domain containing 8.	0.661
COMMD9	COMMD5	ENSLAFP00000001173	ENSLAFP00000008820	COMM domain containing 9.	COMM domain containing 5.	0.978
COMMD9	CUL3	ENSLAFP00000001173	ENSLAFP00000002647	COMM domain containing 9.	Cullin 3; Belongs to the cullin family.	0.519
COMMD9	KBTBD8	ENSLAFP00000001173	ENSLAFP00000002437	COMM domain containing 9.	Kelch repeat and BTB domain containing 8.	0.661
CUL1	COMMD5	ENSLAFP00000002838	ENSLAFP00000008820	Cullin 1; Belongs to the cullin family.	COMM domain containing 5.	0.429
CUL1	CUL3	ENSLAFP00000002838	ENSLAFP00000002647	Cullin 1; Belongs to the cullin family.	Cullin 3; Belongs to the cullin family.	0.886
CUL1	KBTBD8	ENSLAFP00000002838	ENSLAFP00000002437	Cullin 1; Belongs to the cullin family.	Kelch repeat and BTB domain containing 8.	0.697
CUL3	AGO2	ENSLAFP00000002647	ENSLAFP00000010792	Cullin 3; Belongs to the cullin family.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.580
CUL3	COMMD5	ENSLAFP00000002647	ENSLAFP00000008820	Cullin 3; Belongs to the cullin family.	COMM domain containing 5.	0.546
CUL3	COMMD9	ENSLAFP00000002647	ENSLAFP00000001173	Cullin 3; Belongs to the cullin family.	COMM domain containing 9.	0.519
CUL3	CUL1	ENSLAFP00000002647	ENSLAFP00000002838	Cullin 3; Belongs to the cullin family.	Cullin 1; Belongs to the cullin family.	0.886
CUL3	KBTBD8	ENSLAFP00000002647	ENSLAFP00000002437	Cullin 3; Belongs to the cullin family.	Kelch repeat and BTB domain containing 8.	0.952
KBTBD8	AGO2	ENSLAFP00000002437	ENSLAFP00000010792	Kelch repeat and BTB domain containing 8.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.782
KBTBD8	COMMD5	ENSLAFP00000002437	ENSLAFP00000008820	Kelch repeat and BTB domain containing 8.	COMM domain containing 5.	0.661
KBTBD8	COMMD9	ENSLAFP00000002437	ENSLAFP00000001173	Kelch repeat and BTB domain containing 8.	COMM domain containing 9.	0.661

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