STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G3SRD6_LOXAFSulfatase domain-containing protein. (549 aa)    
Predicted Functional Partners:
MED14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.685
SUMF1
Sulfatase modifying factor 1.
  
 0.666
SGSH
N-sulfoglucosamine sulfohydrolase.
  
 0.634
SUMF2
FGE-sulfatase domain-containing protein.
  
 0.581
ARSK
Arylsulfatase family member K.
  
 
0.565
GALNS
Galactosamine (N-acetyl)-6-sulfatase.
  
0.543
ARSB
Arylsulfatase B.
  
0.540
GALC
Galactosylceramidase.
     
 0.534
DHCR7
7-dehydrocholesterol reductase.
   
 
  0.533
ARSJ
Arylsulfatase family member J.
  
0.533
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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