Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SATB2DNA-binding protein SATB. (733 aa)    
Predicted Functional Partners:
TBR1
T-box brain transcription factor 1.
   
 
 0.801
CASP6
Caspase 6; Belongs to the peptidase C14A family.
    
 0.760
UBL5
Ubiquitin like 5.
    
 0.759
CUX1
Homeobox protein cut-like.
    
 
 0.680
UBE2I
Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.679
ATF4
Activating transcription factor 4.
    
 0.654
PAX6
Paired box 6.
      
 0.644
EMX1
Empty spiracles homeobox 1.
   
  
 0.642
RELN
Reelin.
      
 0.623
FEZF2
FEZ family zinc finger 2.
    
 
 0.610
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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