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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SORBS1Sorbin and SH3 domain containing 1. (1291 aa)    
Predicted Functional Partners:
VCL
Vinculin.
   
 0.921
CBL
Cbl proto-oncogene.
    
 0.739
GCH1
GTP cyclohydrolase 1.
    
   0.675
VTA1
Vesicle trafficking 1.
    
   0.675
ITGA1
Integrin subunit alpha 1; Belongs to the integrin alpha chain family.
   
 
 0.671
SORBS3
Sorbin and SH3 domain containing 3.
    
0.626
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
   
 
 0.623
AFDN
Afadin, adherens junction formation factor.
   
 
 0.614
SPART
Spartin.
      
 0.589
TENM1
Teneurin transmembrane protein 1.
    
 
 0.578
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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