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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NKAPNFKB activating protein. (410 aa)    
Predicted Functional Partners:
FAM32A
Family with sequence similarity 32 member A.
    
 0.790
PRKRIP1
PRKR interacting protein 1.
   
 0.776
SLU7
SLU7 homolog, splicing factor.
   
 0.767
SDE2
SDE2 telomere maintenance homolog.
    
 0.752
CWC22
CWC22 spliceosome associated protein homolog.
   
  0.732
CDC40
Cell division cycle 40.
   
  0.695
PPIL1
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
  0.694
C9orf78
Chromosome 9 open reading frame 78.
   
 
  0.666
DDX41
DEAD-box helicase 41.
    
  0.629
CIR1
Corepressor interacting with RBPJ, 1.
   
 
 0.608
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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