STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SH3YL1SH3 and SYLF domain containing 1. (341 aa)    
Predicted Functional Partners:
SH3D19
SH3 domain containing 19.
    
   0.808
SMAP2
Small ArfGAP2.
    
 
 0.715
NLRC5
Uncharacterized protein.
      
 0.691
VPS37B
VPS37B subunit of ESCRT-I.
    
   0.682
ANKRD54
Ankyrin repeat domain 54.
    
 
 0.681
MVK
Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
    
   0.663
POLN
DNA polymerase nu.
      
 0.631
WASL
WASP like actin nucleation promoting factor.
    
 
 0.616
WAS
WASP actin nucleation promoting factor.
    
 
 0.616
PGR
NR LBD domain-containing protein.
    
 
 0.588
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.