Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CRTC1CREB regulated transcription coactivator 1. (611 aa)    
Predicted Functional Partners:
CREB1
cAMP responsive element binding protein 1.
    
 0.910
CRTC3
CREB regulated transcription coactivator 3.
   
 0.883
CRTC2
CREB regulated transcription coactivator 2.
   
 0.881
YWHAZ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.
    
   0.665
YWHAQ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family.
    
   0.664
MAML2
Mastermind like transcriptional coactivator 2.
      
 0.648
G3SLR0_LOXAF
Uncharacterized protein.
    
 0.639
ATF1
Uncharacterized protein.
    
 0.639
SIK2
Salt inducible kinase 2.
    
 0.614
APC
APC regulator of WNT signaling pathway.
      
 0.601
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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