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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MIB1Mindbomb E3 ubiquitin protein ligase 1. (930 aa)    
Predicted Functional Partners:
NHS
NHS actin remodeling regulator.
   
 0.629
ZMYM4
Zinc finger MYM-type containing 4.
   
  0.557
PCM1
Pericentriolar material 1.
    
 0.525
JAG1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
 0.507
MIB2
Mindbomb E3 ubiquitin protein ligase 2.
  
0.456
DLL1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
 0.450
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
 0.450
NEURL1
Neuralized E3 ubiquitin protein ligase 1.
    
 0.445
NEURL1B
Neuralized E3 ubiquitin protein ligase 1B.
    
 0.445
UBA5
Ubiquitin like modifier activating enzyme 5.
   
 0.444
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.