STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ERI3ERI1 exoribonuclease family member 3. (337 aa)    
Predicted Functional Partners:
CCDC24
Coiled-coil domain containing 24.
      
 0.857
TRAPPC4
Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.
   
  
 0.820
TRAPPC1
Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.
   
  
 0.817
SPCS2
Signal peptidase complex subunit 2.
      
 0.814
RNF220
Ring finger protein 220.
      
 0.776
DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]
      
 0.701
DUS3L
tRNA-dihydrouridine(47) synthase [NAD(P)(+)].
 
 
    0.659
SP9
Uncharacterized protein.
      
 0.650
PRNP
Major prion protein; Belongs to the prion family.
    
 
 0.623
GAPVD1
GTPase activating protein and VPS9 domains 1.
      
 0.600
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.