Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIX6SIX homeobox 6. (284 aa)    
Predicted Functional Partners:
VAX2
Ventral anterior homeobox 2.
   
 
 0.813
CNGA3
Cyclic nucleotide gated channel subunit alpha 3.
      
 0.733
TLE1
TLE family member 1, transcriptional corepressor.
    
 
 0.710
NR4A3
Nuclear receptor subfamily 4 group A member 3.
    
 
 0.708
RRS1
Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.
      
 0.668
PAX6
Paired box 6.
   
 
 0.657
DNMBP
Dynamin binding protein.
      
 0.641
CNGB3
Cyclic nucleotide gated channel subunit beta 3.
      
 0.621
OTX2
Orthodenticle homeobox 2.
   
 
 0.608
VSX2
Visual system homeobox 2.
   
  
 0.556
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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