Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF220Ring finger protein 220. (566 aa)    
Predicted Functional Partners:
ZC4H2
Zinc finger C4H2-type containing.
    
 
 0.951
CCDC24
Coiled-coil domain containing 24.
      
 0.886
ERI3
ERI1 exoribonuclease family member 3.
      
 0.776
VRK1
VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily.
    
 0.735
CUL7
Cullin 7; Belongs to the cullin family.
    
 
 0.586
FBXO3
F-box protein 3.
      
 0.580
USP7
Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.
    
 0.568
SLC24A2
Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.560
BCL11A
BAF chromatin remodeling complex subunit BCL11A.
      
 0.555
LRIG3
Leucine rich repeats and immunoglobulin like domains 3.
    
 0.551
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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