STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RABGGTBGeranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (339 aa)    
Predicted Functional Partners:
RABGGTA
Rab geranylgeranyltransferase subunit alpha.
    
 0.999
PTAR1
Protein prenyltransferase alpha subunit repeat containing 1.
    
 0.983
CHM
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.978
PTP4A1
Protein tyrosine phosphatase 4A1.
    
 0.922
PTP4A2
Protein tyrosine phosphatase 4A2.
    
 0.922
RAB1A
RAB1A, member RAS oncogene family.
    
 0.853
RAB1B
RAB1B, member RAS oncogene family.
    
 0.853
YKT6
YKT6 v-SNARE homolog; Belongs to the synaptobrevin family.
    
 
 0.832
PIP5K1C
Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma.
    
   0.782
RAB31
RAB31, member RAS oncogene family.
    
 0.727
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.