STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BEST4Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (379 aa)    
Predicted Functional Partners:
PELO
Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.
 
      0.580
RPE65
Retinoid isomerohydrolase RPE65.
      
 0.568
DEPDC1
DEP domain containing 1.
      
 0.568
TTR
Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
      
 0.538
CA7
Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family.
   
  
 0.534
OTOP2
Otopetrin 2.
   
  
 0.516
MERTK
MER proto-oncogene, tyrosine kinase.
      
 0.442
GLUL
Glutamine synthetase.
    
 
 0.438
RPL13
60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.
      
 0.427
LRRC8A
Leucine rich repeat containing 8 VRAC subunit A.
      
 0.427
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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