Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAVSMitochondrial antiviral signaling protein. (516 aa)    
Predicted Functional Partners:
DDX58
DExD/H-box helicase 58.
    
 0.998
IFIH1
Interferon induced with helicase C domain 1.
    
 0.997
STING1
Transmembrane protein 173.
    
 0.996
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.996
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.995
NLRX1
NLR family member X1.
    
 0.993
TRAF5
TNF receptor-associated factor.
    
 0.989
TBK1
TANK binding kinase 1.
    
 0.986
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.982
EIF2AK2
Eukaryotic translation initiation factor 2 alpha kinase 2.
    
 0.977
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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