STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
UBE2CUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (181 aa)    
Predicted Functional Partners:
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
 0.945
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.901
ANAPC11
RING-type domain-containing protein.
    
 0.895
BIRC5
Baculoviral IAP repeat containing 5.
   
 0.893
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.889
CDC20B
Cell division cycle 20B.
   
 0.885
CDC20
Cell division cycle 20.
   
 0.885
ANAPC2
Anaphase promoting complex subunit 2; Belongs to the cullin family.
    
 0.881
TOP2A
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
 0.876
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.875
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.