STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HECTD2HECT domain E3 ubiquitin protein ligase 2. (687 aa)    
Predicted Functional Partners:
NEURL1B
Neuralized E3 ubiquitin protein ligase 1B.
    
 
 0.646
FAM92A
Family with sequence similarity 92 member A.
   
 0.562
TM2D1
TM2 domain containing 1.
      
 0.553
NIPAL2
NIPA like domain containing 2.
      
 0.535
UBE2L6
Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.532
UBE2L5
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.532
TRIP12
Thyroid hormone receptor interactor 12.
   
 
 0.509
ISG15
ISG15 ubiquitin like modifier.
   
 0.507
NOC3L
Nucleolar complex protein 3 homolog.
      
 0.505
TSC2
TSC complex subunit 2.
    
 0.505
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.