STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUL3Cullin 3; Belongs to the cullin family. (746 aa)    
Predicted Functional Partners:
RBX1
Ring-box 1.
    
 0.998
KEAP1
Kelch like ECH associated protein 1.
    
 0.996
KLHL12
Kelch like family member 12.
    
 0.995
NEDD8
NEDD8 ubiquitin like modifier.
    
 0.993
KLHL3
Kelch like family member 3.
    
 0.982
KLHL20
Kelch like family member 20.
    
 0.978
COPS4
COP9 signalosome subunit 4.
    
 0.977
KLHL21
Kelch like family member 21.
    
 0.976
SPOPL
Speckle type BTB/POZ protein like.
   
 0.975
SPOP
Speckle type BTB/POZ protein.
   
 0.975
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.