STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)    
Predicted Functional Partners:
PRPF6
Pre-mRNA processing factor 6.
    
 0.924
PRPF8
Pre-mRNA processing factor 8.
    
 0.918
EFTUD2
Elongation factor Tu GTP binding domain containing 2.
   
 0.913
DDX23
DEAD-box helicase 23.
    
 0.883
SNRPG
Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
   
 0.863
SNRNP40
Small nuclear ribonucleoprotein U5 subunit 40.
    
 0.863
CD2BP2
CD2 cytoplasmic tail binding protein 2.
   
 0.860
ZMAT2
Zinc finger matrin-type 2.
   
 0.845
LSM2
U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.
   
 0.819
SNRPF
Small nuclear ribonucleoprotein polypeptide F.
   
 0.817
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.