STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CNN3Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (329 aa)    
Predicted Functional Partners:
G3TC70_LOXAF
Uncharacterized protein.
    
 
 0.811
CALB2
Calbindin 2.
   
 0.642
PARP10
Poly [ADP-ribose] polymerase.
   
  
 0.596
ENKUR
Enkurin, TRPC channel interacting protein.
   
 
 0.591
SMTN
Smoothelin.
   
  
 0.567
PLEK
Pleckstrin.
     
 0.531
RSPH1
Radial spoke head component 1.
      
 0.522
EFHB
EF-hand domain family member B.
   
   0.510
WDR1
WD repeat domain 1.
   
 
 0.508
ACTA2
Actin alpha 2, smooth muscle.
   
 0.502
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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