Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZAR1zf-3CxxC domain-containing protein. (190 aa)    
Predicted Functional Partners:
GDF9
Growth differentiation factor 9.
      
 0.797
RFWD3
Ring finger and WD repeat domain 3.
      
 0.619
EIF2B2
Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family.
      
 0.618
NLRP5
NACHT domain-containing protein.
      
 0.565
PADI6
Peptidyl arginine deiminase 6.
      
 0.539
SARDH
Sarcosine dehydrogenase.
      
 0.526
DGKB
Diacylglycerol kinase.
      
 0.526
UCHL1
Ubiquitin carboxyl-terminal hydrolase.
      
 0.516
CD164L2
CD164 molecule like 2.
      
 0.505
MST1R
Macrophage stimulating 1 receptor.
      
 0.504
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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