STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)    
Predicted Functional Partners:
GPI
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.968
PC
Pyruvate carboxylase.
   
 0.953
H6PD
Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.
  
 
 0.952
ENO4
Enolase 4.
  
 0.948
ALDOB
Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.
  
 
 0.946
G6PD
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
  
 
 0.941
LDHB
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.938
ALDOA
Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.
  
 
 0.933
ALDOC
Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.
  
 
 0.929
TALDO1
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 0.927
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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