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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C8AComplement C8 alpha chain. (541 aa)    
Predicted Functional Partners:
C8G
Complement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family.
   
 0.990
C8B
Complement C8 beta chain.
  
0.977
C9
Complement C9.
   
0.794
C7
Uncharacterized protein.
   
0.764
C6
Complement C6.
   
0.761
XPNPEP3
X-prolyl aminopeptidase 3.
   
  
 0.693
EDNRB
Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.665
C5
Complement C5.
   
 0.661
C1R
Complement C1r; Belongs to the peptidase S1 family.
   
 
 0.652
F13B
Coagulation factor XIII B chain.
   
  
 0.619
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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