STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMPD2Sphingomyelin phosphodiesterase 2. (416 aa)    
Predicted Functional Partners:
NSMAF
Neutral sphingomyelinase activation associated factor.
     
 0.975
UGCG
UDP-glucose ceramide glucosyltransferase.
     
 0.966
SMPD1
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
     
 0.963
ASAH2
Neutral ceramidase.
     
 0.956
ASAH1
N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family.
     
 0.946
ACER2
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
    
 0.943
ACER1
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
    
 0.943
SGMS2
Sphingomyelin synthase 2.
     
 0.942
SGMS1
Sphingomyelin synthase 1.
     
 0.942
DEGS1
Delta 4-desaturase, sphingolipid 1.
     
 0.941
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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