STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SETD2SET domain containing 2, histone lysine methyltransferase. (1941 aa)    
Predicted Functional Partners:
ASH1L
ASH1 like histone lysine methyltransferase.
   
 
 0.962
KMT2E
Lysine methyltransferase 2E.
   
 0.947
DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
   
 0.924
IWS1
Interacts with SUPT6H, CTD assembly factor 1.
   
 
 0.901
SETD1A
SET domain containing 1A, histone lysine methyltransferase.
   
 0.900
SETD1B
SET domain containing 1B, histone lysine methyltransferase.
   
 0.900
SMYD2
SET and MYND domain containing 2.
     
 0.897
POLR2A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.887
CAMKMT
Calmodulin-lysine N-methyltransferase.
     
 0.886
SUV39H1
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
   
 0.882
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.