Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MROH8Maestro heat like repeat family member 8. (958 aa)    
Predicted Functional Partners:
LOXHD1
Lipoxygenase homology domains 1.
      
 0.557
POLR3F
DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
      
 0.509
PTPRQ
Protein tyrosine phosphatase receptor type Q.
      
 0.502
PLA2G1B
Phospholipase A(2).
      
 0.493
OGFOD3
2-oxoglutarate and iron dependent oxygenase domain containing 3.
      
 0.455
C3AR1
Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family.
  
     0.445
AK3
Adenylate kinase 3; Belongs to the adenylate kinase family.
   
  
 0.419
POLR2C
RNA polymerase II subunit C.
      
 0.419
SLC33A1
Solute carrier family 33 member 1.
   
  
 0.417
ART5
NAD(P)(+)--arginine ADP-ribosyltransferase.
  
     0.413
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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