Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RAP2CRAP2C, member of RAS oncogene family. (183 aa)    
Predicted Functional Partners:
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
 0.898
RHOB
Ras homolog family member B.
   
 0.792
RHOA
Ras homolog family member A.
   
 0.792
RAPGEF4
Rap guanine nucleotide exchange factor 4.
   
 0.699
AFDN
Afadin, adherens junction formation factor.
    
 0.628
RHOC
Uncharacterized protein.
   
 0.596
ADCY5
Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
    
 0.583
EEFSEC
Eukaryotic elongation factor, selenocysteine-tRNA specific.
      
 0.580
RAPGEF6
Uncharacterized protein.
    
 0.578
NOS1AP
Nitric oxide synthase 1 adaptor protein.
    
 0.575
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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