Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SLC7A3Solute carrier family 7 member 3. (615 aa)    
Predicted Functional Partners:
MST1R
Macrophage stimulating 1 receptor.
    
  0.446
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]
    
  0.446
SVOPL
SVOP like.
   
  
 0.434
CCDC114
Coiled-coil domain containing 114.
     
 0.431
PLPP4
Phospholipid phosphatase 4.
   
  
 0.424
G3TTT3_LOXAF
Uncharacterized protein.
  
 
0.421
SLC25A35
Solute carrier family 25 member 35; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.419
SLC7A9
Solute carrier family 7 member 9.
  
 
0.414
CDX4
Caudal type homeobox 4.
   
  
 0.410
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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