Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSC22D3TSC22 domain family member 3. (196 aa)    
Predicted Functional Partners:
NRBP1
Nuclear receptor binding protein 1.
    
 
 0.936
G3U3L2_LOXAF
Uncharacterized protein.
   
 
 0.870
TSC22D1
TSC22 domain family member 1.
   
 
 0.850
SGK1
Non-specific serine/threonine protein kinase.
   
 0.828
NRBP2
Uncharacterized protein.
    
 
 0.802
TCFL5
Transcription factor like 5.
      
 0.720
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.711
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.711
FAM117B
Family with sequence similarity 117 member B.
    
 
 0.655
SGK2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 0.620
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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