Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NEK5Protein kinase domain-containing protein. (234 aa)    
Predicted Functional Partners:
G3TBG8_LOXAF
Uncharacterized protein.
 
      0.899
G3U5M8_LOXAF
Uncharacterized protein.
 
    
 0.895
VPS36
Vacuolar protein sorting 36 homolog.
      
 0.504
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
  
0.493
NEK2
NIMA related kinase 2.
   
 
 0.492
RSPH9
Radial spoke head 9 homolog.
    
 
 0.478
ALS2
Alsin Rho guanine nucleotide exchange factor ALS2.
    
 0.475
CENPF
Centromere protein F.
   
 0.460
DLGAP5
DLG associated protein 5.
   
  
 0.444
NDC80
NDC80 kinetochore complex component.
   
  
 0.421
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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