STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUL1Cullin 1; Belongs to the cullin family. (776 aa)    
Predicted Functional Partners:
SKP2
S-phase kinase associated protein 2.
    
 0.999
RBX1
Ring-box 1.
    
 0.999
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
   
 0.999
FBXW11
F-box and WD repeat domain containing 11.
   
 0.996
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
   
 0.993
NEDD8
NEDD8 ubiquitin like modifier.
    
 0.991
UBXN7
UBX domain-containing protein 7.
   
 0.986
CDKN1B
Cyclin dependent kinase inhibitor 1B.
    
 0.985
FBXW7
F-box and WD repeat domain containing 7.
    
 0.982
CDKN1A
Cyclin dependent kinase inhibitor 1A.
    
 0.977
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.