STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TBC1D23TBC1 domain family member 23. (666 aa)    
Predicted Functional Partners:
FAM91A1
Family with sequence similarity 91 member A1.
   
 
 0.911
OSGEP
Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
    
   0.839
GLRX3
Glutaredoxin 3.
    
   0.839
API5
Apoptosis inhibitor 5.
   
   0.807
C17orf75
Chromosome 17 open reading frame 75.
      
 0.807
TBC1D20
TBC1 domain family member 20.
      
 0.598
ANKRD50
Ankyrin repeat domain 50.
      
 0.575
AP1AR
Adaptor related protein complex 1 associated regulatory protein.
      
 0.555
RAB18
RAB18, member RAS oncogene family.
      
 0.550
SPRYD7
SPRY domain containing 7.
      
 0.545
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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