Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CDR2Cerebellar degeneration related protein 2. (460 aa)    
Predicted Functional Partners:
CDR2L
Cerebellar degeneration related protein 2 like.
    
   0.927
KTN1
Kinectin 1.
    
   0.810
C4orf46
Chromosome 4 open reading frame 46.
    
   0.803
TCHP
Uncharacterized protein.
    
   0.779
CDT1
Chromatin licensing and DNA replication factor 1.
   
   0.678
IGSF3
Immunoglobulin superfamily member 3.
    
   0.665
MYC
Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
    
 
 0.620
CBS
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
      
 0.570
CD101
CD101 molecule.
    
   0.505
SIKE1
Suppressor of IKBKE 1.
    
   0.503
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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