Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BROXBRO1 domain and CAAX motif containing. (410 aa)    
Predicted Functional Partners:
LOC100655308
Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
   
 0.862
CHMP5
Charged multivesicular body protein 5.
   
 0.861
CHMP6
Charged multivesicular body protein 6.
    
 0.841
CHMP4C
Charged multivesicular body protein 4C.
   
 0.729
CHMP4B
Charged multivesicular body protein 4B.
   
 0.729
VPS4B
Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.
   
 0.670
STAM2
Signal transducing adaptor molecule 2.
   
 
 0.631
VPS4A
Uncharacterized protein; Belongs to the AAA ATPase family.
   
 0.614
PIP4K2A
Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha.
      
 0.594
RHBDD2
Rhomboid domain containing 2.
      
 0.588
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.