Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RFX6Regulatory factor X6. (931 aa)    
Predicted Functional Partners:
MLXIPL
MLX interacting protein like.
      
 0.655
RFXANK
Regulatory factor X associated ankyrin containing protein.
   
 0.623
PCSK1
Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.
      
 0.618
RFXAP
Regulatory factor X associated protein.
    
 0.605
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.594
PAX4
Paired box 4.
   
  
 0.564
GHRL
Ghrelin and obestatin prepropeptide.
      
 0.556
CHEK2
Checkpoint kinase 2.
   
 0.526
NKX2-2
NK2 homeobox 2.
      
 0.491
PTF1A
Pancreas associated transcription factor 1a.
      
 0.491
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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