Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLHL12Kelch like family member 12. (568 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.995
FBXL17
F-box and leucine rich repeat protein 17.
    
 0.957
RBX1
Ring-box 1.
    
 0.954
SEC31B
SEC31 homolog B, COPII coat complex component.
    
 0.893
SEC31A
SEC31 homolog A, COPII coat complex component.
    
 0.893
PEF1
Penta-EF-hand domain containing 1.
    
 0.890
PDCD6
Programmed cell death 6.
    
 0.890
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
    
 0.888
DRD4
Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.
    
 0.864
KLHL26
Kelch like family member 26.
    
 0.838
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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