close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RC3H2Ring finger and CCCH-type domains 2. (1189 aa)    
Predicted Functional Partners:
MYSM1
Myb like, SWIRM and MPN domains 1.
   
   0.729
CNOT1
CCR4-NOT transcription complex subunit 1.
   
 
 0.698
TRIP12
Thyroid hormone receptor interactor 12.
   
    0.681
HELZ
Helicase with zinc finger.
   
 
 0.641
ATXN2L
Ataxin 2 like.
   
 
 0.631
AFF4
AF4/FMR2 family member 4.
   
 
 0.565
XRN1
5'-3' exoribonuclease 1.
   
 
 0.559
LTN1
Listerin E3 ubiquitin protein ligase 1.
   
  
 0.526
RC3H1
Ring finger and CCCH-type domains 1.
  
 
  
0.525
UBR1
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
  
 0.521
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.