Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LIPCLipase C, hepatic type. (490 aa)    
Predicted Functional Partners:
LMF1
Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.
    
 0.945
ACSL1
Acyl-CoA synthetase long chain family member 1.
    
 0.935
ACSL5
Acyl-CoA synthetase long chain family member 5.
    
 0.935
ACSL6
AMP-binding domain-containing protein.
    
 0.928
LIPF
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
   
 0.926
LPL
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
  
 
 
0.915
ACSBG1
Acyl-CoA synthetase bubblegum family member 1.
    
 0.907
ACSBG2
Acyl-CoA synthetase bubblegum family member 2.
    
 0.907
PNPLA3
Patatin like phospholipase domain containing 3.
     
 0.902
LPIN1
Lipin 1.
   
 0.895
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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