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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLX2Distal-less homeobox 2. (333 aa)    
Predicted Functional Partners:
DLX1
Distal-less homeobox 1.
   
 
0.792
TBR1
T-box brain transcription factor 1.
   
 
 0.647
LHX6
LIM homeobox 6.
   
  
 0.597
IRX2
Iroquois homeobox 2.
   
 
 0.596
IRX1
Iroquois homeobox 1.
   
 
 0.591
LEF1
Lymphoid enhancer binding factor 1.
    
 0.569
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.563
ASCL2
Achaete-scute family bHLH transcription factor 2.
      
 0.524
RAG2
Recombination activating 2.
      
 0.515
BMP7
Bone morphogenetic protein 7.
     
 0.506
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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